NanoActive RES

Nanoactive Res is a novel resveratrol nanoliposome preparation (NanoLiposomal Resveratrol).
Product Name: Nano Liposomal Res, Nanoactive Res; BioActive Resveratrol; NanoActive Resveratrol CAS: 501-36-0

Description: Resveratrol (“Res”) is a non-flavonoid polyphenolic compound. A Japanese called Tokaoka was the first one who obtained it by separating it from the roots of Veratrum granginorumin 1940. With the in-depth study of resveratrol, it has been shown that resveratrol has a wide range of activities such as anti-cancer, anti-oxidation, anti-bacteria and anti-inflammation which can be broadly used in medicine, health care products, food, cosmetics and other fields. Resveratrol has many targets in the skin, so it can be used as a skincare product to produce whitening, anti-wrinkle, anti-bacteria, anti-inflammation, acne curing and anti-aging effects. It is an emerging natural active substance with high efficiency. However, resveratrol is hardly soluble in water while easy to be oxidized and discolored, which limits its application in cosmetics. The nano actives, developed with the nano-transmission system (NDS), has a particle size of less than 30nm, and enables the resveratrol to be steadily encapsulated in nano-carriers, greatly improving the absorption efficiency and bioavailability. This overcomes the original defects while maintaining the advantages with a more convenient and wider range of uses.

 

 

 

 

 

 

   Resveratrol

                   

 

 

 

 

 

 

 

  Number of  papers on resveratrol in PUBMED over years

 

 

 

 

 

 

 

Resveratrol can effectively prolong life span

Skincare effect

Resveratrol is a natural antioxidant present in plants. Its antioxidant capacity is 20-50 times that of L-C. If applied simultaneously with L-C, the effect will be multiplied. Resveratrol inhibits collagenase, reduces collagen degradation, promotes collagen proliferation, and firms skin. Resveratrol allows cells to enhance their self-defense enzymes, thereby repairing damaged DNA, while effectively inhibiting oncogenic proteins produced by UVB exposure. Resveratrol can effectively inhibit melanin synthesis by reacting with multiple targets required for melanin synthesis, thereby achieving whitening and brightening effect.

 

 

 

 

Resveratrol inhibits melanin synthesis through multiple targets

 

Features

  • NanoActive RES uses FDA GRAS grade materials for high safety
  • NanoActive RES is stable to heat, pH and shearing, so it is convenient to use.
  • NanoActive RES greatly improves the stability and bioavailability of resveratrol
  • NanoActive RES can improve the stability of other active matters in the product and facilitate absorption
  • NanoActive RES is 100% water soluble and 100% oil soluble (amphiphilic), allowing a wide range of uses.

 

Applications

  • Promote collagen synthesis, improve skin thickness and elasticity, remove wrinkles, and firm your skin
  • Inhibit melanin synthesis, reduce pigmentation and whiten your skin
  • Eliminate free radicals and confront skin aging
  • Promote wound healing and reduce scars
  • Cure acne and reduce acne marks.
  • Anti-bacteria, diminish inflammation and sensitization, and provide analgesic effects
  • Prevent scarring and fibrosis

 

Use:Add it at room temperature. You may heat it to over 40℃ to speed up the dissolution. Recommended dosage: 1-5%. The optimum pH range of the system is 3.0-6.5, and the finished product should be protected from direct exposure to sunlight (using opaque packaging). It is recommended to add UV absorber to day care products.

Storage: Keep it away from light at a temperature below 25℃.

Experimental proof

 

                     Resveratrol inhibits intracellular melanin synthesis

 

                      Resveratrol tyrosinase activity is superior to kojic acid

 

Low concentration of resveratrol (0.001%) can reduce B16F10 cell melanin by 50%

      Two-week application can provide noticeable whitening effect

 

                       Resveratrol has obvious anti-wrinkle effect

Resveratrol (0.001%) is effective in treating acne

Before RES treatment                                  After RES (0.001%) treatment

Posted in Anti-aging, Innovative Formulation, product, Whitening and freckle elimination.