NanoActive ISO is a novel soy isoflavone nanoliposome preparation (NanoLiposomal ISO).
Product Name: Nano Liposomal Soy Isoflaves; Nanoactive Soy Isoflavones; BioaActive Soy Isoflavones; Soluble Soy Isoflavones
CAS: 574-12-9
Description: Isoflavone is one of the flavonoids. It can be found mainly in legumes and is a secondary metabolite formed during the growth of soybeans. With a structure similar to estrogen, it is also called phytoestrogen, which can make up for the estrogen deficiency of women after 30 years old, increase skin moisture and elasticity, relieve menopausal syndrome and improve osteoporosis, thus enabling women to regain youthful charm. Soy isoflavone have been proved to be effective in anti-aging, and have a hormonal effect without side effects. However, due to the water-insolubility of soy isoflavone, it is difficult to be applied in cosmetics. NanoActive ISO is a new generation of nanoscale carrier containing soy isoflavone, which converts soy isoflavone into a completely water soluble form. By improving solubility, NanoActive ISO can easily penetrates into your skin and exerts the full effects of soy isoflavone.
Soy Isoflavone and Estradiol Structure
Soy isoflavone is featured with a similar activity to estrogen, and its main benefits to the skin include:
- Eliminating oxygen free radicals and resist aging:Promote the metabolism of skin cells and maintain skin elasticity. Prevent mature skin from degenerating due to lack of hormones
- Whitening:Inhibit tyrosinase as well as diminish chloasma and melasma
- Removing wrinkle:Promote collagen synthesis
- Skin Firming and Bust Beauty:Phytoestrogens supplement the body’s estrogen
- Inhibition to Androgen: Reduce the secretion of grease (acne skin), inhibit hair growth in arms and legs (depilatory), and promote scalp hair growth (thin hair)
NanoActive ISO encapsulates soy isoflavone in a nanoscale carrier composed of a polar lipid layer and a lipophilic core.
NanoActive is water-soluble even when it contains such an oil-soluble active as soy isoflavone. The solution is completely clear and transparent so NanoActive ISO is applicable to clear hydrogel formulations.
Formulation Advantages:
- Shearing stability
- pH stability
- Heat stability
- Improvement on skin texture
- Low viscosity
NanoActive technology improves the permeability of soy isoflavone by converting it to a water-soluble form, thereby enhancing the efficacy.
Cell Regulation of Collagen Formation and Degradation (estrogen-promoted synthesis)
The degradation signal is marked in red and the formation one in green.
E, estrogen; ER, estrogen receptor; EGFR, epidermal growth factor receptor;
TK, tyrosine kinase
Nano soy isoflavone increases skin thickness
Increase skin moisture
Improve skin firmness
Application
Anti-wrinkle and anti-aging cream, whitening, eliminating freckles and wrinkles, nourishing hair, facilitating hair growth, and depilatory cream
Formulation guidelines
Recommended dosage: 1% – 3%
Solubility: water and oil
pH: 2-6
Heat stability: stable
Electrolyte stability: no identified incompatibility
Shelf life: 1 year
Storage: Store with its original packaging at room temperature (<25 ° C).