Pterocarpus Santalinus Wood Extract Nanoemulsion
Being a precious kind of wood, rosewood can be developed for skincare. It has been recorded in Shizhen Li’s “Compendium of Materia Medica” in the Ming Dynasty as a valuable Chinese herbal medicine that helps blood circulation and removes blood stasis. Study has found that pterostilbene is one of the most important active ingredients in rosewood. Pterostilbene is a structural homologue of resveratrol. Recently, it has been found to increase the activity of Sirtuin 1 (deacetylase) by 12 times, which helps delaying aging and prolonging lifespan. Compared with resveratrol, pterostilbene can be more easily absorbed, with good bio-pharmaceutical response, more stable metabolism, stronger effects of anti-oxidation and anti-cell proliferation, a longer half-life (over 7 times that of resveratrol), better clinical effect. It can better reduce NF-κB, iNOS and other anti-inflammatory markers. It can also selectively inhibit COX-2, with an antibacterial ability 5-10 times that of resveratrol. Pterostilbene can effectively inhibit the formation of melanin, brighten the skin, and protect the skin from UV damage. With the pterostilbene nanoemulsion developed by nano-transport system, Puripharm effectively solve the application problems of low solubility, poor stability and easy discoloration so that it can be easily applied to various skincare products.
Pterostilbene is a derivative in which the third and the fifth of phenolic hydroxyl groups of resveratrol are substituted by methoxy groups. In recent years, it has been increasingly recognized for its potential effects of anti-cancer, anti-oxidation, anti-inflammatory and anti-diabetic. Although the amount and position of the hydroxyl group are usually the main factors determining the biological activity of the natural polyphenol product, pterostilbene, with only the 4-position hydroxyl group, exhibits an antioxidant activity equal to or even stronger than that of resveratrol. In the cell-free system, pterostilbene has an antioxidant capacity similar to that of resveratrol. In terms of protecting erythrocyte membrane from lipid peroxidation, pterostilbene is significantly more effective (IC50 = (44.5 ± 7.8) μmol / L) than resveratrol. Pterostilbene is also known as “second-generation resveratrol”.
Resveratrol Pterostilbene
Pterostilbene (Pter) is more effective in preventing ultraviolet rays from causing inflammation than resveratrol (Resv).
Protective effects of Pter and Resv from skin cancer caused by UV irradiation
The main problems hindering Pterostilbene’s application in cosmetics are its chemical instability, discoloration and low solubility. Rosewood extract nanoemulsion developed with nano drug-delivery technologysolves the above problems well while retaining pterostilbene’s intrinsic biological activity. Therefore it can be easily and effectively used in various cosmetics, better absorbed, and function better in whitening, anti-inflammatory and sunburn repair.
Nanoemulsion is more active than traditional preparations
Product Features ：
- pTeroNano uses FDA GRAS grade materials for higher safety.
- pTeroNano is stable to heat, pH, and cuts, so it is convenient to use.
- pTeroNano A huge improvement in pterostilbene’s solubility, stability and bioavailability of pterostilbene
- pTeroNano It can improve the stability of other active substances in the product and facilitate absorption
Product use: add under low temperature , pTeroNano has a small amount of positive charge (helps nanocarriers attach to and be absorbed by the skin). If there is much negative charge in the formulation system, you must add pTeroNano before diluting it with pure water, or adjust the dosage, or purchase customized uncharged product from the manufacturer.
Recommended dosage ：0.5-5%。Better effect with products containing nano-retinene, nano-astaxanthin, etc.
Product Storage: keep it away from light at a temperature below 25℃.