Magnolia officinalis is an important herb of traditional Chinese medicine, which has been included in the Chinese pharmacopoeia. Magnolia officinalis barks contain two anti-inflammatory isomers, magnolol and honokiol. Magnolia officinalis barks have been used in Asia for more than a thousand years in the treatment of qi stagnation (lassitude), digestive disorders, anxiety, and allergic diseases. Magnolia officinalis extract nanoemulsion uses nano-technology to encapsulate magnolol and honokiol, the main active matters of magnolia officinalis extract, to solve the problem of solubility, making it more stable and easier to be absorbed so that it can better perform its activity of anti-inflammation, anti-aging, anti-aging, anti-bacterial, etc.
Magnolol and honokiol a traditional Chinese medicine Magnolia officinalis
Wide Application of Magnolia Officinalis Extract in Medicine
Inflammation is the first body response to infection or irritation, manifested by partially increased blood flow, migration and activation of immune cells in the affected area, release of numerous free radicals, and destruction towards normal tissues. Ideally, inflammation can clear the infection and then resolve spontaneously, allowing normal tissues to rebuild. But inflammation can become chronic (for example, the infection does not completely disappear, or the inflammatory response becomes very sensitive, or the inflammatory response is caused by an autoimmune response). In addition, as we grow older, we are more and more prone to chronic inflammation. Chronic inflammation caused by free radicals will particularly accelerate the aging process.
Inflammation Caused by Free Radicals
Chronic inflammation is a key risk factor as we age, and it is now considered as one of the key risk factors for aging diseases such as heart disease and stroke. Inflammation is also deemed as the cause of some age-related common neurodegenerative diseases such as Alzheimer’s and Parkinson’s. Studies have found that when a person is feeble, there is usually an excess of one or more inflammatory factors inside him, such as TNF-a (tumor necrosis factor), IL-6, IL-1 (b), or IL-8 (leukocyte hormone). Inflammatory aging becomes a major challenge for human health.
Inflammatory Aging
Studies have shown that the main active matters in the magnolia officinalis extract are magnolol and honokiol. Magnolol and honokiol are effective in removing oxygen free radicals from the body. By inhibiting the activation of NF-ĸB (transcription factor), magnolol and honokiol produce a synergistic anti-inflammatory effect. In addition, they have antioxidant, antibacterial and anti-angiogenic effects while reducing harmful substances. Magnolol and honokiol also have a very strong anti-allergic effect.
Magnolia officinalis has strong antibacterial effect. Its antibacterial spectrum is wide, and the antibacterial property is stable, which will not be easily damaged by heat, acid and alkali. It has a strong inhibitory effect on Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, etc., and has an inhibitory effect on common pathogenic skin fungi.
Better Anti-propionibacteria Activity of Magnolol and Honokiol than Erythromycin
Minimum Inhibitory Concentration (MIC) of Magnolol and Honokiol against Propionibacterium
Higer Transdermal Efficiency of Nanoemulsion Encapsulated Active Matters than Traditional Preparations
Product Features:
- Magnano uses materials of FDA GRAS class, so it is very safe
- Magnano is stable to heat, pH and cuts, so it is convenient to use
- Magnano greatly improve the solubility, stability and bioavailability of plant polyphenols.
- Magnano can improve the stability of other active matters in the product and facilitate absorption
- Magnano itself has good antibacterial activity without preservatives
Wide Application of Magnano in Skincare Products
Use of Product:Add it at a low temperature. It is suitable for anti-aging, anti-inflammation, anti-oxidation products, etc.
Recommended dosage:0.1-5%。Better effect with products containing nano-astaxanthin, etc.
Storage of Product: keep it away from light at a temperature below 25℃.